Gamma E Complex

Gamme E Complex

Gamma E is gaining attention as a highly significant and potent form of Vitamin E.

Source Naturals brings you a better way of life with breakthrough research in Vitamin E, the second most-recommended daily supplement today after multivitamins. No doubt you’ve heard how important Vitamin E is to your health, but did you know that all Vitamin E supplements are not alike?

Most people are familiar with a type of Vitamin E chemically known as d-alpha tocopherol. Yet, Vitamin E is actually a general name for a whole family of compounds—and Gamma E is proving to be one of the more effective forms. Make Gamma E 400 Complex part of your health plan for more complete nutrition.

Antioxidant and Cardiovascular Support

Antioxidants like Vitamin E have been shown to help neutralize destructive free radicals and support cardiovascular health by preventing the oxidation of cholesterol.† Oxidized cholesterol is an unstable molecule that damages the integrity of arteries.

Additionally, preliminary studies show that Vitamin E may inhibit foam cell formation in in-vitro cell cultures. Foam cells are macrophages that pick up oxidized lipids and form fatty streaks in the artery walls, contributing to plaque formation.

Gamma E - A More Potent Antioxidant

Vitamin E refers to eight related, lipid soluble antioxidant compounds widely distributed in plants and especially in vegetable oils: the tocopherol subfamily (alpha-, beta-, gamma- and delta-) and tocotrienol subfamily (alpha-tocotrienol, beta-tocotrienol, gamma-tocotrienol and delta-tocotrienol).

These vital antioxidants are effective against free radicals inside the cell because they are fat-soluble and can pass through the lipid layer of the cell membrane.

Since alpha tocopherol has historically been the major form sold, gamma tocopherol received little attention. The combination of Vitamin E tocopherols, particularly those with a high gamma to alpha ratio is a more potent antioxidant than alpha-tocopherol alone.

Gamma tocopherol can help protect against peroxynitrite free radicals and lipid peroxidative damage. Research has shown that this form also helps to inhibit cyclooxygenase (COX-2) activity, the production of irritating prostaglandin E2, and protect against nitrogen-based free radicals, as well as afford improved cardiovascular support.†

Gamma tocopherol has also been shown to support the activity of the alpha form as well as offer activity of its own. Gamma supplementation can result in an increase in alpha tocopherol concentrations in the body, whereas taking alpha only may suppress or decrease tissue gamma tocopherol.

Research indicates that a ratio of gamma to alpha-tocopherol greater than 1:1 increases levels of both tocopherols in the body and that alpha-tocopherol alone may not be adequate to combat oxidative stress. Gamma-E 400 offers a 3:1 gamma to alpha-tocopherol ratio (200 IU equals 133 mg) and also contains tocotrienols from palm fruit which provides high concentrations of all four tocotrienols: alpha, beta, gamma, and delta. This product also includes sesame oil as a base, which is a rich source of gamma-tocopherol.

Vitamin E Deficiency

Epidemiological research and clinical trials have suggested that Vitamin E can help maintain healthy blood sugar levels, support healthy cholesterol levels, provide positive effects on the growth and regulation of cells and tissues, and even nerve transmission. A deficiency can have a negative impact on these functions.

Researchers previously thought that deficiencies of Vitamin E were rare but a large population based study showed that suboptimal levels might be quite common. According to this study, African-Americans feel most of the impact, with 41% having sub-optimal levels of Vitamin E in their blood, compared with 28% of Mexican Americans, and 26% of Caucasians. Optimal level refers to levels in research studies associated with cardiovascular benefits. Many people, especially African-Americans, may benefit from the extra cardiovascular support offered by Vitamin E.†

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References

1. Ford, E; Sowell, A. Serum a-tocopherol status in the United States Population: findings from the third national health and nutrition examination survey. American Journal of Epidemiology 150 (3):290-300. ©1999 The Johns Hopkins University School of Hygiene and Public Health.


2. Li, D et al. 2001. Different isoforms of tocopherols enhance nitric oxide synthase phosphorylation and inhibit human platelet aggregation and lipid peroxidation: implications in therapy with vitamin E. Journal of Cardiovascular Pharmacology and Therapeutics. 6 (2): 155-161.


3. Jiang, Qing et al. 2001. Gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention. American Journal of Clinical Nutrition. 74:714-22.


4. Nesaretnam, et al. 2000. Tocotrienols inhibit growth of ZR-75-1 breast cancer cells. International Journal of Food Sciences and Nutrition. 51, S95-S103.