7-Keto DHEA

7-Keto® DHEA Metabolite

NOTE: Australia, Canada, and Brazil prohibit the import of any products containing DHEA. Other countries may as well - check with your customs office. Please do not include this product in any order shipped to those countries.

7-Keto DHEA is considered by nutritional scientists to be among the most effective compounds for healthy aging and overall well being. Produced in the body, DHEA (dehydroepiandrosterone) is a natural hormone responsible for many vital system functions. Its production declines with age, however, and low levels of DHEA have been linked to lack of energy, loss of memory, weight gain, and decreased immunity.†

Before its active metabolite 7-Keto DHEA was discovered, supplementation with DHEA had mixed results. However, current research has shown that 7-Keto DHEA has all the benefits of its parent compound (DHEA), without the downside. 7-Keto DHEA may retain and enhance the thermogenic, neurological, and immunological activity of DHEA, but it cannot be metabolized into unwanted testosterone or estrogens.†

A safe and more active form of an essential hormone, Source Naturals 7-Keto DHEA is nutritional science at its best—quality you can trust to help protect against the ravages of time.†

Beneficial Functions of DHEA

The most plentiful adrenal steroid in the blood of humans, DHEA (dehydroepiandrosterone) is manufactured in the adrenal glands, as well as in the testes and in the brain. Produced abundantly during youth, DHEA levels peak at about age 25, but decrease by more than 50% at around age 55. Because DHEA is integral to such a wide variety of important functions, this decline may leave the body vulnerable to various health problems.

Researchers have discovered critical links between DHEA and improvement in:

• Maintaining a healthy body weight†
• Brain function†
• Immune function†
• Bone deposition†
• Cardiovascular health†
• Percentage of muscle mass†
• A decrease in the percentage of body fat†

DHEA plays a role in controlling age-related increases in blood glucose and insulin resistance. This is a crucial factor in maintaining youthful tissues in the circulatory system, as well as for preventing storage of excess body fat due to insulin resistance. Elderly patients with cognitive difficulties show significantly lower blood levels of DHEA than control groups. Supplemental DHEA was shown to increase physical and psychological well-being in men and women, including better sleep and ability to handle stress.†

DHEA’s diverse biological activities may result from its anti-cortisol action. Cortisol is produced by the adrenal glands in response to stress, but our stress-inducing culture is causing a vast overload of cortisol in many people. This excess cortisol can damage cells and tissues, and contribute to the aging process.

7-Keto DHEA is More Active than DHEA

Researchers have identified 7-Keto DHEA as an active ingredient of DHEA. When tested, it significantly outperformed its parent compound. Animal studies found 7-Keto DHEA to be 2.5 times more active than DHEA at increasing liver thermogenic enzymes. Optimal mitochondrial enzyme activity is crucial to the production of cellular energy for mental and physical activity. As an active inducer of thermogenic enzymes, 7-Keto DHEA provides support for weight management or strength training.†

DHEA and Immunity

7 Keto DHEA has been shown to help boost the immune system by increasing the production of specialized white blood cells. Since some health professionals feel that increasing DHEA levels may benefit those with an overactive immune response.¹†

7-Keto DHEA and Sex Hormones

Although DHEA is an intermediate in the biosynthesis of estrogens and testosterone, 7-Keto DHEA is not. Therefore 7-Keto DHEA cannot be metabolized into active estrogenic or androgenic sex hormones and does not cause the imbalances and undesirable side effects of its parent compound.†

7-Keto DHEA and Weight Loss

7-Keto is a non-stimulant, thermogenic agent that has been clinically proven in randomized, double-blind, placebo-controlled trials to promote healthy body weight when added to a moderate diet and exercise program.†

• Supplementation with 7-Keto can safely promote thermogenesis,thereby supporting the maintenance of healthy body weightdagger;
• Clinical studies of 7-Keto DHEA demonstrated increases in metabolic rate and improvement in body mass index†
• Helps increase metabolism without stimulants†
• Shown to induce thermogenic enzymes in preclinical research†

A Safe Strategy to Aging Well

Research has shown that supplementation of 7-Keto DHEA is well tolerated. Evaluated for safety in human clinical trials and animal studies, 7-Keto DHEA had no adverse effects, even at doses up to 200 mg/day. Adding 7-Keto DHEA to your supplement regimen is a profound yet easy way to minimize the wear and tear over time on your body, and has the potential to put more life in your years.†

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References

1. 7-Keto "The Key to Healthy Aging" Test.
2. Bobyleva, V. et al. 1997. The Effects of the Ergosteroid 3-Acetyl-7-Oxo-Dehydroepiandrosterone on mitochondrial membrane potential: possible relationship to thermogenesis. Arch Biochem and Biophys 341:122-128.
3. Lardy, H. et al. 1998. Ergosteroids 3 II: Biologically active metabolites and synthetic derivatives of dehydroepiandrosterone. Steroids 63:158-65.
4. Lardy, H. et al. 1995. Ergosteroids: Induction of thermogenic enzymes in liver of rats treated with steroids derived from DHEA. Proc Natl Acad Sci 92:6617-6619.
5. Morales, A. et al. 1994. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. J Clin Endocrinol Metab 78:1360-67.